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Enhanced Oxygen Utilization Efficiency With Concomitant Activation of AMPK-TBC1D1 Signaling Nexus in Cyclophilin-D Conditional Knockout Mice

We have previously reported in HEK 293 T cells and in constitutive cyclophilin-D (Cyp-D) knockout (KO) mice that Cyp-D ablation downregulates oxygen consumption (VO(2)) and triggers an adaptive response that manifest in higher exercise endurance with less VO(2). This adaptive response involves a met...

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Detalles Bibliográficos
Autores principales:	Radhakrishnan, Jeejabai, Baetiong, Alvin, Gazmuri, Raúl J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692870/ https://www.ncbi.nlm.nih.gov/pubmed/34955879 http://dx.doi.org/10.3389/fphys.2021.756659

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