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Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice

Histone H4 lysine16 acetylation (H4K16Ac) modulates chromatin structure by serving as a switch from a repressive to a transcriptionally active state. This euchromatin mark is associated with active transcription. In this study, we investigated the effects of H4K16Ac on the expression of pro-fibrotic...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiangyu, Liu, Hui, Zhou, Jennifer Q, Krick, Stefanie, Barnes, Jarrod W, Thannickal, Victor J, Sanders, Yan Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692895/ https://www.ncbi.nlm.nih.gov/pubmed/34976199 http://dx.doi.org/10.7150/thno.62760

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