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Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric cancer

Background: The protumor activities of cancer-associated fibroblasts (CAFs) suggest that they are potential therapeutic targets for the treatment of cancer. The mechanism of CAF heterogeneity in gastric cancer (GC) remains unclear and has slowed translational advances in targeting CAFs. Therefore, a...

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Detalles Bibliográficos
Autores principales: Li, Xuechun, Sun, Zhao, Peng, Gongxin, Xiao, Yi, Guo, Junchao, Wu, Bin, Li, Xiaoyi, Zhou, Weixun, Li, Jiarui, Li, Zhe, Bai, Chunmei, Zhao, Lin, Han, Qin, Zhao, Robert Chunhua, Wang, Xiaoyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692898/
https://www.ncbi.nlm.nih.gov/pubmed/34976204
http://dx.doi.org/10.7150/thno.60540