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Ion drugs for precise orthotopic tumor management by in situ the generation of toxic ion and drug pools
Background: Asymmetric intracellular and extracellular ionic gradients are critical to the survivability of mammalian cells. Given the importance of manganese (Mn(2+)), calcium (Ca(2+)), and bicarbonate (HCO(3)(-)) ions, any alteration of the ion-content balance could induce a series of cellular res...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692900/ https://www.ncbi.nlm.nih.gov/pubmed/34976210 http://dx.doi.org/10.7150/thno.66468 |