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A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

When several life-prolonging drugs are indicated for cancer treatment, predictive drug-response tumor biomarkers are essential to guide management. Most conventional biomarkers are based on bulk tissue analysis, which cannot address the complexity of single-cell heterogeneity responsible for drug re...

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Detalles Bibliográficos
Autores principales: Champagne, Audrey, Jain, Pallavi, Vélot, Lauriane, Riopel, Julie, Lefebvre, Véronique, Neveu, Bertrand, Pouliot, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692902/
https://www.ncbi.nlm.nih.gov/pubmed/34976196
http://dx.doi.org/10.7150/thno.63744