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A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy
When several life-prolonging drugs are indicated for cancer treatment, predictive drug-response tumor biomarkers are essential to guide management. Most conventional biomarkers are based on bulk tissue analysis, which cannot address the complexity of single-cell heterogeneity responsible for drug re...
Autores principales: | Champagne, Audrey, Jain, Pallavi, Vélot, Lauriane, Riopel, Julie, Lefebvre, Véronique, Neveu, Bertrand, Pouliot, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692902/ https://www.ncbi.nlm.nih.gov/pubmed/34976196 http://dx.doi.org/10.7150/thno.63744 |
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