Loss of function of GATA3 induces basal-like mammary tumors

Purpose: GATA3 is a transcription factor essential for mammary luminal epithelial cell differentiation. Expression of GATA3 is absent or significantly reduced in basal-like breast cancers. Gata3 loss-of-function impairs cell proliferation, making it difficult to investigate the role of GATA3 deficie...

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Detalles Bibliográficos
Autores principales: Bai, Feng, Zheng, Chenglong, Liu, Xiong, Chan, Ho Lam, Liu, Shiqin, Ma, Jinshan, Ren, Sijia, Zhu, Wei-Guo, Pei, Xin-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692904/
https://www.ncbi.nlm.nih.gov/pubmed/34976209
http://dx.doi.org/10.7150/thno.65796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692904/
https://www.ncbi.nlm.nih.gov/pubmed/34976209
http://dx.doi.org/10.7150/thno.65796

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