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Loss of function of GATA3 induces basal-like mammary tumors
Purpose: GATA3 is a transcription factor essential for mammary luminal epithelial cell differentiation. Expression of GATA3 is absent or significantly reduced in basal-like breast cancers. Gata3 loss-of-function impairs cell proliferation, making it difficult to investigate the role of GATA3 deficie...
Autores principales: | Bai, Feng, Zheng, Chenglong, Liu, Xiong, Chan, Ho Lam, Liu, Shiqin, Ma, Jinshan, Ren, Sijia, Zhu, Wei-Guo, Pei, Xin-Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692904/ https://www.ncbi.nlm.nih.gov/pubmed/34976209 http://dx.doi.org/10.7150/thno.65796 |
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