HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity

Breast cancer is the most common female malignancy in both the developed and developing world. Doxorubicin is one of the most commonly used chemotherapies for breast cancer. Unfortunately, up to 60% of survivors report long-term chemotherapy-induced cognitive dysfunction (CICD) characterized by defi...

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Detalles Bibliográficos
Autores principales: McAlpin, Blake R, Mahalingam, Rajasekaran, Singh, Anand K, Dharmaraj, Shruti, Chrisikos, Taylor T, Boukelmoune, Nabila, Kavelaars, Annemieke, Heijnen, Cobi J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692908/
https://www.ncbi.nlm.nih.gov/pubmed/34976203
http://dx.doi.org/10.7150/thno.67410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692908/
https://www.ncbi.nlm.nih.gov/pubmed/34976203
http://dx.doi.org/10.7150/thno.67410

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