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HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity
Breast cancer is the most common female malignancy in both the developed and developing world. Doxorubicin is one of the most commonly used chemotherapies for breast cancer. Unfortunately, up to 60% of survivors report long-term chemotherapy-induced cognitive dysfunction (CICD) characterized by defi...
Autores principales: | McAlpin, Blake R, Mahalingam, Rajasekaran, Singh, Anand K, Dharmaraj, Shruti, Chrisikos, Taylor T, Boukelmoune, Nabila, Kavelaars, Annemieke, Heijnen, Cobi J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692908/ https://www.ncbi.nlm.nih.gov/pubmed/34976203 http://dx.doi.org/10.7150/thno.67410 |
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