Suppression of breast cancer-associated bone loss with osteoblast proteomes via Hsp90ab1/moesin-mediated inhibition of TGFβ/FN1/CD44 signaling

Background: Bone is a frequent site of metastases from breast cancer, but existing therapeutic options are not satisfactory. Although osteoblasts have active roles in cancer progression by assisting the vicious bone-destructive cycle, we employed a counterintuitive approach of activating pro-tumorig...

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Detalles Bibliográficos
Autores principales: Sun, Xun, Li, Kexin, Hase, Misato, Zha, Rongrong, Feng, Yan, Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692912/
https://www.ncbi.nlm.nih.gov/pubmed/34976221
http://dx.doi.org/10.7150/thno.66148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692912/
https://www.ncbi.nlm.nih.gov/pubmed/34976221
http://dx.doi.org/10.7150/thno.66148

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