5-aza-2′-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages

Background: 5-aza-2'-deoxycytidine (5Aza), a DNA methyltransferase (DNMT) inhibitor, could activate tumor adaptive immunity to inhibit tumor progression. However, the molecular mechanisms by which 5Aza regulates tumor immune microenvironment are still not fully understood. Methods: The role of...

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Detalles Bibliográficos
Autores principales: Shi, Rongchen, Zhao, Kun, Wang, Teng, Yuan, Jing, Zhang, Dapeng, Xiang, Wei, Qian, Jin, Luo, Na, Zhou, Yong, Tang, Bo, Li, Chuan, Miao, Hongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692916/
https://www.ncbi.nlm.nih.gov/pubmed/34976218
http://dx.doi.org/10.7150/thno.66420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692916/
https://www.ncbi.nlm.nih.gov/pubmed/34976218
http://dx.doi.org/10.7150/thno.66420

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