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HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitment

Rationale: Tumor-associated macrophages (TAMs), generally displaying the pro-tumor M2-like phenotype, strongly influence the progression of colorectal cancer (CRC) via their immunosuppressive activities. The high-mobility gene group A2 (HMGA2), an oncoprotein, is aberrantly overexpressed in CRC cell...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wang, Jian, Zhao, Jiahui, Wang, Hao, Chen, Jing, Wu, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692921/
https://www.ncbi.nlm.nih.gov/pubmed/34976223
http://dx.doi.org/10.7150/thno.65411