Cargando…

HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitment

Rationale: Tumor-associated macrophages (TAMs), generally displaying the pro-tumor M2-like phenotype, strongly influence the progression of colorectal cancer (CRC) via their immunosuppressive activities. The high-mobility gene group A2 (HMGA2), an oncoprotein, is aberrantly overexpressed in CRC cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xin, Wang, Jian, Zhao, Jiahui, Wang, Hao, Chen, Jing, Wu, Jingjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692921/ https://www.ncbi.nlm.nih.gov/pubmed/34976223 http://dx.doi.org/10.7150/thno.65411

Ejemplares similares

Emerging roles for HMGA2 in colorectal cancer
por: Wang, Xin, et al.
Publicado: (2020)

HMGA1 Promotes Macrophage Recruitment via Activation of NF-κB-CCL2 Signaling in Hepatocellular Carcinoma
por: Chen, Junming, et al.
Publicado: (2022)

HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway
por: Xu, Xi, et al.
Publicado: (2018)

ER-α36 Promotes the Malignant Progression of Cervical Cancer Mediated by Estrogen via HMGA2
por: Wang, Chunyan, et al.
Publicado: (2021)

Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer
por: Klemke, Luisa, et al.
Publicado: (2021)

MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway
por: Chen, Wankun, et al.
Publicado: (2016)

JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis
por: Chen, Siyuan, et al.
Publicado: (2023)

N(6)-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis
por: Chen, Ri-Xin, et al.
Publicado: (2019)

MYC-regulated pseudogene HMGA1P6 promotes ovarian cancer malignancy via augmenting the oncogenic HMGA1/2
por: Tian, Xiaoxue, et al.
Publicado: (2020)

HMGA1B/2 transcriptionally activated-POU1F1 facilitates gastric carcinoma metastasis via CXCL12/CXCR4 axis-mediated macrophage polarization
por: Tang, Cheng, et al.
Publicado: (2021)

Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression
por: Xu, Jiuhui, et al.
Publicado: (2023)

Tumor-associated neutrophils and macrophages interaction contributes to intrahepatic cholangiocarcinoma progression by activating STAT3
por: Zhou, Zhengjun, et al.
Publicado: (2021)

HMGA2 regulates acute myeloid leukemia progression and sensitivity to daunorubicin via Wnt/β-catenin signaling
por: Yang, Shuo, et al.
Publicado: (2019)

Attenuated expression of SNF5 facilitates progression of bladder cancer via STAT3 activation
por: Ding, Hua, et al.
Publicado: (2021)

TIMELESS Promotes Tumor Progression by Enhancing Macrophages Recruitment in Ovarian Cancer
por: Xing, Xin, et al.
Publicado: (2021)

Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer
por: Tang, Hui, et al.
Publicado: (2020)

RNA-Mediated Regulation of HMGA1 Function
por: Benecke, Arndt G., et al.
Publicado: (2015)

Circular RNA 100146 Promotes Colorectal Cancer Progression by the MicroRNA 149/HMGA2 Axis
por: Liu, Kunpeng, et al.
Publicado: (2021)

M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway
por: Yao, Rong-Rong, et al.
Publicado: (2018)

LINC00963 affects the development of colorectal cancer via MiR-532-3p/HMGA2 axis
por: Ye, Jinjun, et al.
Publicado: (2021)

Correction to: Attenuated expression of SNF5 facilitates progression of bladder cancer via STAT3 activation
por: Ding, Hua, et al.
Publicado: (2022)

Tumor-Linked Macrophages Promote HCC Development by Mediating the CCAT1/Let-7b/HMGA2 Signaling Pathway
por: Deng, Liang, et al.
Publicado: (2020)

Overexpression of hsa_circ_0008274 inhibited the progression of lung adenocarcinoma by regulating HMGA2 via sponging miR‐578
por: Wang, Maolong, et al.
Publicado: (2021)

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer
por: Ekanem, Titus Ime, et al.
Publicado: (2020)

circUBAP2 regulates osteosarcoma progression via the miR-204-3p/HMGA2 axis
por: Ma, Weiguo, et al.
Publicado: (2021)

Glucosamine facilitates cardiac ischemic recovery via recruiting Ly6C(low) monocytes in a STAT1 and O‐GlcNAcylation‐dependent fashion
por: Zhou, Wenjing, et al.
Publicado: (2022)

Lupeol inhibits osteosarcoma progression by up-regulation of HMGA2 via regulating miR-212-3p
por: Zhong, Jinghua, et al.
Publicado: (2020)

Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway
por: Cui, Can, et al.
Publicado: (2019)

Tumor-Associated Macrophages Recruit CCR6(+) Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice
por: Liu, Jinlin, et al.
Publicado: (2011)

CCL2/CCR2 Axis Promotes the Progression of Salivary Adenoid Cystic Carcinoma via Recruiting and Reprogramming the Tumor-Associated Macrophages
por: Yang, Zihui, et al.
Publicado: (2019)

Calmodulin 2 Facilitates Angiogenesis and Metastasis of Gastric Cancer via STAT3/HIF-1A/VEGF-A Mediated Macrophage Polarization
por: Mu, Ganggang, et al.
Publicado: (2021)

MicroRNA‐9 exerts antitumor effects on hepatocellular carcinoma progression by targeting HMGA2
por: Xu, Xiangang, et al.
Publicado: (2019)

HMGA2 promotes the migration and invasion of gallbladder cancer cells and HMGA2 knockdown inhibits angiogenesis via targeting VEGFA
por: Yan, Jun, et al.
Publicado: (2022)

The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3′UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2
por: Wang, Yuan, et al.
Publicado: (2017)

Cynaropicrin Shows Antitumor Progression Potential in Colorectal Cancer Through Mediation of the LIFR/STATs Axis
por: Zheng, Dandan, et al.
Publicado: (2021)

GRP75‐mediated upregulation of HMGA1 stimulates stage I lung adenocarcinoma progression by activating JNK/c‐JUN signaling
por: Qiao, Guo‐Bing, et al.
Publicado: (2021)

HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters
por: Eilebrecht, Sebastian, et al.
Publicado: (2014)

METTL3-mediated m(6)A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial–mesenchymal transition
por: Wang, Yuwei, et al.
Publicado: (2023)

Circ_0035483 Functions as a Tumor Promoter in Renal Cell Carcinoma via the miR-31-5p-Mediated HMGA1 Upregulation
por: Liu, Zheng, et al.
Publicado: (2021)

lncRNA MIR210HG promotes the progression of endometrial cancer by sponging miR-337-3p/137 via the HMGA2-TGF-β/Wnt pathway
por: Ma, Jian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_opkbpu8p9ok232ahkni9da41mq