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Sequence and functional characterization of a public HIV-specific antibody clonotype

Public antibody clonotypes shared among multiple individuals have been identified for several pathogens. However, little is known about the determinants of antibody “publicness”. Here, we characterize the sequence and functional properties of antibodies from a public clonotype targeting the CD4 bind...

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Detalles Bibliográficos
Autores principales: Murji, Amyn A., Raju, Nagarajan, Qin, Juliana S., Kaldine, Haajira, Janowska, Katarzyna, Fechter, Emilee Friedman, Mapengo, Rutendo, Scheepers, Cathrine, Setliff, Ian, Acharya, Priyamvada, Morris, Lynn, Georgiev, Ivelin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692997/
https://www.ncbi.nlm.nih.gov/pubmed/34984325
http://dx.doi.org/10.1016/j.isci.2021.103564