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ScaffComb: A Phenotype‐Based Framework for Drug Combination Virtual Screening in Large‐Scale Chemical Datasets

Combinational therapy is used for a long time in cancer treatment to overcome drug resistance related to monotherapy. Increased pharmacological data and the rapid development of deep learning methods have enabled the construction of models to predict and screen drug pairs. However, the size of drug...

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Detalles Bibliográficos
Autores principales: Ye, Zhaofeng, Chen, Fengling, Zeng, Jiangyang, Gao, Juntao, Zhang, Michael Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693048/
https://www.ncbi.nlm.nih.gov/pubmed/34723439
http://dx.doi.org/10.1002/advs.202102092