Cargando…

Position‐Scanning Peptide Libraries as Particle Immunogens for Improving CD8(+) T‐Cell Responses

Short peptides reflecting major histocompatibility complex (MHC) class I (MHC‐I) epitopes frequently lack sufficient immunogenicity to induce robust antigen (Ag)‐specific CD8(+) T cell responses. In the current work, it is demonstrated that position‐scanning peptide libraries themselves can serve as...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Xuedan, Zhou, Shiqi, Quinn, Breandan, Huang, Wei‐Chiao, Jahagirdar, Dushyant, Vega, Michael, Ortega, Joaquin, Long, Mark D., Ito, Fumito, Abrams, Scott I., Lovell, Jonathan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693074/
https://www.ncbi.nlm.nih.gov/pubmed/34716694
http://dx.doi.org/10.1002/advs.202103023