Paraspeckle Protein NONO Promotes TAZ Phase Separation in the Nucleus to Drive the Oncogenic Transcriptional Program

The Hippo pathway effector TAZ promotes cellular growth, survival, and stemness through regulating gene transcription. Recent studies suggest that TAZ liquid–liquid phase separation (LLPS) compartmentalizes key cofactors to activate transcription. However, how TAZ LLPS is achieved remains unknown. H...

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Detalles Bibliográficos
Autores principales: Wei, Yiju, Luo, Huacheng, Yee, Patricia P., Zhang, Lijun, Liu, Zhijun, Zheng, Haiyan, Zhang, Lei, Anderson, Benjamin, Tang, Miaolu, Huang, Suming, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693076/
https://www.ncbi.nlm.nih.gov/pubmed/34716691
http://dx.doi.org/10.1002/advs.202102653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693076/
https://www.ncbi.nlm.nih.gov/pubmed/34716691
http://dx.doi.org/10.1002/advs.202102653

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