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Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model

Osteoarthritis (OA) is a serious joint inflammation that leads to cartilage degeneration and joint dysfunction. Mesenchymal stem cells (MSCs) are used as a cell-based therapy that showed promising results in promoting cartilage repair. However, recent studies and clinical trials explored unsatisfied...

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Detalles Bibliográficos
Autores principales: Alahdal, Murad, Huang, Rongxiang, Duan, Li, Zhiqin, Deng, Hongwei, Ouyang, Li, Wencui, Wang, Daping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693178/
https://www.ncbi.nlm.nih.gov/pubmed/34956209
http://dx.doi.org/10.3389/fimmu.2021.781185