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Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model
Osteoarthritis (OA) is a serious joint inflammation that leads to cartilage degeneration and joint dysfunction. Mesenchymal stem cells (MSCs) are used as a cell-based therapy that showed promising results in promoting cartilage repair. However, recent studies and clinical trials explored unsatisfied...
Autores principales: | Alahdal, Murad, Huang, Rongxiang, Duan, Li, Zhiqin, Deng, Hongwei, Ouyang, Li, Wencui, Wang, Daping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693178/ https://www.ncbi.nlm.nih.gov/pubmed/34956209 http://dx.doi.org/10.3389/fimmu.2021.781185 |
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