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Utilizing in silico and in vitro methods to identify possible binding sites of a novel ligand against Pseudomonas aeruginosa phospholipase toxin ExoU

Multi-drug resistant infections caused by the opportunistic pathogen, Pseudomonas aeruginosa (P. aeruginosa), are a continuing problem that contribute to morbidity and mortality in immunocompromised hosts such as cystic fibrosis (CF), wound and burn patients. The bacterial toxin ExoU is one of four...

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Detalles Bibliográficos
Autores principales: Chamberlain, Krista, Johnson, Mya, Reid, Terry-Elinor, Springer, Tzvia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693347/
https://www.ncbi.nlm.nih.gov/pubmed/34984240
http://dx.doi.org/10.1016/j.bbrep.2021.101188