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Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges

The discovery of immune checkpoints (ICs) and the development of specific blockers to relieve immune effector cells from this inhibiting mechanism has changed the view of anti-cancer therapy. In addition to cytotoxic T lymphocyte antigen 4 (CTLA4) and programmed death 1 (PD1), classical ICs of T lym...

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Detalles Bibliográficos
Autores principales: Poggi, Alessandro, Zocchi, Maria Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693432/
https://www.ncbi.nlm.nih.gov/pubmed/34977340
http://dx.doi.org/10.1016/j.omto.2021.11.016