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HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy

Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses that persist despite antiretroviral therapy (ART). Understanding the burden, genetic diversity, and longevity of persisting proviruses in diverse individuals with HIV is critical to this goal, but these...

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Detalles Bibliográficos
Autores principales: Omondi, F. Harrison, Sudderuddin, Hanwei, Shahid, Aniqa, Kinloch, Natalie N., Jones, Bradley R., Miller, Rachel L., Tsai, Olivia, MacMillan, Daniel, Trocha, Alicja, Brockman, Mark A., Brumme, Chanson J., Joy, Jeffrey B., Liang, Richard, Walker, Bruce D., Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693448/
https://www.ncbi.nlm.nih.gov/pubmed/34781741
http://dx.doi.org/10.1128/mBio.02490-21