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Structural plasticity in the loop region of engineered lipocalins with novel ligand specificities, so-called Anticalins

Anticalins are generated via combinatorial protein design on the basis of the lipocalin protein scaffold and constitute a novel class of small and robust engineered binding proteins that offer prospects for applications in medical therapy as well as in vivo diagnostics as an alternative to antibodie...

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Detalles Bibliográficos
Autores principales: Achatz, S., Jarasch, A., Skerra, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693463/
https://www.ncbi.nlm.nih.gov/pubmed/34988429
http://dx.doi.org/10.1016/j.yjsbx.2021.100054