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Emergence and patterning dynamics of mouse-definitive endoderm

The segregation of definitive endoderm (DE) from bipotent mesendoderm progenitors leads to the formation of two distinct germ layers. Dissecting DE commitment and onset has been challenging as it occurs within a narrow spatiotemporal window in the embryo. Here, we employ a dual Bra/Sox17 reporter ce...

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Detalles Bibliográficos
Autores principales: Pour, Maayan, Kumar, Abhishek Sampath, Farag, Naama, Bolondi, Adriano, Kretzmer, Helene, Walther, Maria, Wittler, Lars, Meissner, Alexander, Nachman, Iftach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693470/
https://www.ncbi.nlm.nih.gov/pubmed/34988400
http://dx.doi.org/10.1016/j.isci.2021.103556