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YY1 activates EMI2 and promotes the progression of cholangiocarcinoma through the PI3K/Akt signaling axis

BACKGROUND: Cholangiocarcinoma (CCA) is one of the deadliest cancers of the digestive tract. The prognosis of CCA is poor and the 5-year survival rate is low. Bioinformatic analysis showed that early mitotic inhibitor 2 (EMI2) was overexpressed in CCA but the underlying mechanism is not known. METHO...

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Detalles Bibliográficos
Autores principales: Zhou, Shuai, Qu, Kang Lin, Li, Jin Ang, Chen, Shi Lei, Zhang, Yi Gang, Zhu, Chao, Jin, Hao, Wang, Yong, Pang, Qing, Liu, Hui Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693494/
https://www.ncbi.nlm.nih.gov/pubmed/34933678
http://dx.doi.org/10.1186/s12935-021-02328-6