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Microtissues from mesenchymal stem cells and siRNA-loaded cross-linked gelatin microparticles for bone regeneration

The aim of this study was the evaluation of cross-linked gelatin microparticles (cGM) as substrates for osteogenic cell culture to assemble 3D microtissues and their use as delivery system for siRNA to cells in these assemblies. In a 2D transwell cultivation system, we found that cGM are capable to...

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Detalles Bibliográficos
Autores principales: Hinkelmann, Sandra, Springwald, Alexandra H., Starke, Annett, Kalwa, Hermann, Wölk, Christian, Hacker, Michael C., Schulz-Siegmund, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693629/
https://www.ncbi.nlm.nih.gov/pubmed/34988418
http://dx.doi.org/10.1016/j.mtbio.2021.100190