Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts

Human induced pluripotent stem cells (hiPSCs) allow in vitro study of genetic diseases and hold potential for personalized stem cell therapy. Gene editing, precisely modifying specifically targeted loci, represents a valuable tool for different hiPSC applications. This is especially useful in monoge...

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Detalles Bibliográficos
Autores principales: Jalil, Sami, Keskinen, Timo, Maldonado, Rocío, Sokka, Joonas, Trokovic, Ras, Otonkoski, Timo, Wartiovaara, Kirmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693657/
https://www.ncbi.nlm.nih.gov/pubmed/34822772
http://dx.doi.org/10.1016/j.stemcr.2021.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693657/
https://www.ncbi.nlm.nih.gov/pubmed/34822772
http://dx.doi.org/10.1016/j.stemcr.2021.10.017

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