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Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts
Human induced pluripotent stem cells (hiPSCs) allow in vitro study of genetic diseases and hold potential for personalized stem cell therapy. Gene editing, precisely modifying specifically targeted loci, represents a valuable tool for different hiPSC applications. This is especially useful in monoge...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693657/ https://www.ncbi.nlm.nih.gov/pubmed/34822772 http://dx.doi.org/10.1016/j.stemcr.2021.10.017 |