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Light-induced efficient and residue-selective bioconjugation of native proteins via indazolone formation

Chemical modification of proteins has emerged as a powerful tool to realize enormous applications, such as development of novel biologics and functional studies of individual protein. We report a light-induced lysine-selective native protein conjugation approach via indazolone formation, conferring...

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Detalles Bibliográficos
Autores principales: Guo, An-Di, Wu, Ke-Huan, Chen, Xiao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693682/
https://www.ncbi.nlm.nih.gov/pubmed/35424183
http://dx.doi.org/10.1039/d0ra10154k