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Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease

New neurons are abnormal in the adult hippocampus of Alzheimer's disease (AD) mouse models. The effects of modulating adult neurogenesis on AD pathogenesis differ from study to study. We reported recently that ablation of adult neural stem cells (aNSCs) was associated with improved memory in AD...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqin, Wei, Xiaojie, Mei, Yufei, Wang, Dongpi, Wang, Jing, Zhang, Yiping, Li, Xuekun, Gu, Yan, Peng, Guoping, Sun, Binggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693766/
https://www.ncbi.nlm.nih.gov/pubmed/34861165
http://dx.doi.org/10.1016/j.stemcr.2021.11.003