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Identification and enhancing production of a novel macrolide compound in engineered Streptomyces peucetius

Streptomyces peucetius produces doxorubicin and daunorubicin, which are important anticancer drugs. In this study, we activate peucemycin, a new antibacterial compound, using an OSMAC strategy. In general, bioactive compounds are produced in a higher amount at room temperature; however, in this stud...

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Detalles Bibliográficos
Autores principales: Pham, Van Thuy Thi, Nguyen, Hue Thi, Nguyen, Chung Thanh, Choi, Ye Seul, Dhakal, Dipesh, Kim, Tae-Su, Jung, Hye Jin, Yamaguchi, Tokutaro, Sohng, Jae Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693821/
https://www.ncbi.nlm.nih.gov/pubmed/35424263
http://dx.doi.org/10.1039/d0ra06099b