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Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation

Autophagy is a conserved intracellular degradation pathway exerting various cytoprotective and homeostatic functions by using de novo double-membrane vesicle (autophagosome) formation to target a wide range of cytoplasmic material for vacuolar/lysosomal degradation. The Atg1 kinase is one of its key...

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Detalles Bibliográficos
Autores principales: Schreiber, Anne, Collins, Ben C., Davis, Colin, Enchev, Radoslav I., Sedra, Angie, D’Antuono, Rocco, Aebersold, Ruedi, Peter, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693860/
https://www.ncbi.nlm.nih.gov/pubmed/34798055
http://dx.doi.org/10.1016/j.molcel.2021.10.024