The two-Cys-type TetR repressor GbaA confers resistance under disulfide and electrophile stress in Staphylococcus aureus

Staphylococcus aureus has to cope with oxidative and electrophile stress during host-pathogen interactions. The TetR-family repressor GbaA was shown to sense electrophiles, such as N-ethylmaleimide (NEM) via monothiol mechanisms of the two conserved Cys55 or Cys104 residues in vitro. In this study,...

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Detalles Bibliográficos
Autores principales: Van Loi, Vu, Busche, Tobias, Fritsch, Verena Nadin, Weise, Christoph, Gruhlke, Martin Clemens Horst, Slusarenko, Alan John, Kalinowski, Jörn, Antelmann, Haike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693949/
https://www.ncbi.nlm.nih.gov/pubmed/34678418
http://dx.doi.org/10.1016/j.freeradbiomed.2021.10.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693949/
https://www.ncbi.nlm.nih.gov/pubmed/34678418
http://dx.doi.org/10.1016/j.freeradbiomed.2021.10.024

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