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Pyk2 regulates cell-edge protrusion dynamics by interacting with Crk

Focal adhesion kinase (FAK) is well established as a regulator of cell migration, but whether and how the closely related proline-rich tyrosine kinase 2 (Pyk2) regulates fibroblast motility is still under debate. Using mouse embryonic fibroblasts (MEFs) from Pyk2(–/–) mice, we show here, for the fir...

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Detalles Bibliográficos
Autores principales: Lukic, Nikola, Lapetina, Stefanie, Grobe, Hanna, Srikanth, Kolluru D., Twafra, Shams, Solomon, Jonathan, Sneh, Tal, Gendler, Michal, Zaidel-Bar, Ronen, Gil-Henn, Hava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693953/
https://www.ncbi.nlm.nih.gov/pubmed/34432482
http://dx.doi.org/10.1091/mbc.E20-10-0640