Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3

Cyclin D3 regulates the G1/S transition and is frequently overexpressed in several cancer types including breast cancer, where it promotes tumor progression. Here we show that a cytoskeletal protein keratin 19 (K19) physically interacts with a serine/threonine kinase GSK3β and prevents GSK3β-depende...

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Detalles Bibliográficos
Autores principales: Sharma, Pooja, Tiufekchiev, Sarah, Lising, Victoria, Chung, Seung Woo, Suk, Jung Soo, Chung, Byung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693971/
https://www.ncbi.nlm.nih.gov/pubmed/34406791
http://dx.doi.org/10.1091/mbc.E21-05-0255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693971/
https://www.ncbi.nlm.nih.gov/pubmed/34406791
http://dx.doi.org/10.1091/mbc.E21-05-0255

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