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Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3
Cyclin D3 regulates the G1/S transition and is frequently overexpressed in several cancer types including breast cancer, where it promotes tumor progression. Here we show that a cytoskeletal protein keratin 19 (K19) physically interacts with a serine/threonine kinase GSK3β and prevents GSK3β-depende...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693971/ https://www.ncbi.nlm.nih.gov/pubmed/34406791 http://dx.doi.org/10.1091/mbc.E21-05-0255 |