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Nucleoporins’ exclusive amino acid sequence features regulate their transient interaction with and selectivity of cargo complexes in the nuclear pore

Nucleocytoplasmic traffic of nucleic acids and proteins across the nuclear envelop via the nuclear pore complexes (NPCs) is vital for eukaryotic cells. NPCs screen transported macromolecules based on their morphology and surface chemistry. This selective nature of the NPC-mediated traffic is essenti...

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Detalles Bibliográficos
Autores principales: Peyro, Mohaddeseh, Dickson, Andrew M., Mofrad, Mohammad R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8693974/
https://www.ncbi.nlm.nih.gov/pubmed/34473567
http://dx.doi.org/10.1091/mbc.E21-04-0161