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Binding of inhibitors to the monomeric and dimeric SARS-CoV-2 Mpro

SARS-CoV-2 rapidly infects millions of people worldwide since December 2019. There is still no effective treatment for the virus, resulting in the death of more than one million patients. Inhibiting the activity of SARS-CoV-2 main protease (Mpro), 3C-like protease (3CLP), is able to block the viral...

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Detalles Bibliográficos
Autores principales: Tam, Nguyen Minh, Nam, Pham Cam, Quang, Duong Tuan, Tung, Nguyen Thanh, Vu, Van V., Ngo, Son Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694027/
https://www.ncbi.nlm.nih.gov/pubmed/35424256
http://dx.doi.org/10.1039/d0ra09858b