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Disruption of a ∼23–24 nucleotide small RNA pathway elevates DNA damage responses in Tetrahymena thermophila

Endogenous RNA interference (RNAi) pathways regulate a wide range of cellular processes in diverse eukaryotes, yet in the ciliated eukaryote, Tetrahymena thermophila, the cellular purpose of RNAi pathways that generate ∼23–24 nucleotide (nt) small (s)RNAs has remained unknown. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Lee, Suzanne R., Pollard, Daniel A., Galati, Domenico F., Kelly, Megan L., Miller, Brian, Mong, Christina, Morris, Megan N., Roberts-Nygren, Kerry, Kapler, Geoffrey M., Zinkgraf, Matthew, Dang, Hung Q., Branham, Erica, Sasser, Jason, Tessier, Erin, Yoshiyama, Courtney, Matsumoto, Maya, Turman, Gaea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694037/
https://www.ncbi.nlm.nih.gov/pubmed/34010017
http://dx.doi.org/10.1091/mbc.E20-10-0631