Cargando…

Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking

The α-actinin family of actin cross-linking proteins have been implicated in driving tumor cell metastasis through regulation of the actin cytoskeleton; however, there has been little investigation into whether these proteins can influence tumor cell growth. We demonstrate that α-actinin 1 and 4 are...

Descripción completa

Detalles Bibliográficos
Autores principales: Burton, Kevin M., Johnson, Katherine M., Krueger, Eugene W., Razidlo, Gina L., McNiven, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694038/
https://www.ncbi.nlm.nih.gov/pubmed/34010028
http://dx.doi.org/10.1091/mbc.E20-12-0755