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Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane

Sterols are important lipid components of the plasma membrane (PM) in eukaryotic cells, but it is unknown how the PM retains sterols at a high concentration. Phospholipids are asymmetrically distributed in the PM, and phospholipid flippases play an important role in generating this phospholipid asym...

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Detalles Bibliográficos
Autores principales: Kishimoto, Takuma, Mioka, Tetsuo, Itoh, Eriko, Williams, David E., Andersen, Raymond J., Tanaka, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694040/
https://www.ncbi.nlm.nih.gov/pubmed/34038161
http://dx.doi.org/10.1091/mbc.E20-11-0699