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Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder characterized by the loss of nigrostriatal dopaminergic neurons. Mounting evidence suggests that Nrf2 is a promising target for neuroprotective interventions in PD. However, electrophilic chemical properties of the ca...

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Detalles Bibliográficos
Autores principales: Ahuja, Manuj, Ammal Kaidery, Navneet, Attucks, Otis C., McDade, Erin, Hushpulian, Dmitry M., Gaisin, Arsen, Gaisina, Irina, Ahn, Young Hoon, Nikulin, Sergey, Poloznikov, Andrey, Gazaryan, Irina, Yamamoto, Masayuki, Matsumoto, Mitsuyo, Igarashi, Kazuhiko, Sharma, Sudarshana M., Thomas, Bobby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694049/
https://www.ncbi.nlm.nih.gov/pubmed/34737234
http://dx.doi.org/10.1073/pnas.2111643118