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A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development

Normally, dendritic size is established prior to adolescence and then remains relatively constant into adulthood due to a homeostatic balance between growth and retraction pathways. However, schizophrenia is characterized by accelerated reductions of cerebral cortex gray matter volume and onset of c...

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Detalles Bibliográficos
Autores principales: Grubisha, Melanie J., Sun, Tao, Eisenman, Leanna, Erickson, Susan L., Chou, Shinny-yi, Helmer, Cassandra D., Trudgen, Melody T., Ding, Ying, Homanics, Gregg E., Penzes, Peter, Wills, Zachary P., Sweet, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694055/
https://www.ncbi.nlm.nih.gov/pubmed/34848542
http://dx.doi.org/10.1073/pnas.2022546118