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A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development
Normally, dendritic size is established prior to adolescence and then remains relatively constant into adulthood due to a homeostatic balance between growth and retraction pathways. However, schizophrenia is characterized by accelerated reductions of cerebral cortex gray matter volume and onset of c...
Autores principales: | Grubisha, Melanie J., Sun, Tao, Eisenman, Leanna, Erickson, Susan L., Chou, Shinny-yi, Helmer, Cassandra D., Trudgen, Melody T., Ding, Ying, Homanics, Gregg E., Penzes, Peter, Wills, Zachary P., Sweet, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694055/ https://www.ncbi.nlm.nih.gov/pubmed/34848542 http://dx.doi.org/10.1073/pnas.2022546118 |
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