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Structural dynamics in the evolution of a bilobed protein scaffold

Novel biophysical tools allow the structural dynamics of proteins and the regulation of such dynamics by binding partners to be explored in unprecedented detail. Although this has provided critical insights into protein function, the means by which structural dynamics direct protein evolution remain...

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Detalles Bibliográficos
Autores principales: Gouridis, Giorgos, Muthahari, Yusran A., de Boer, Marijn, Griffith, Douglas A., Tsirigotaki, Alexandra, Tassis, Konstantinos, Zijlstra, Niels, Xu, Ruixue, Eleftheriadis, Nikolaos, Sugijo, Yovin, Zacharias, Martin, Dömling, Alexander, Karamanou, Spyridoula, Pozidis, Charalambos, Economou, Anastassios, Cordes, Thorben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694067/
https://www.ncbi.nlm.nih.gov/pubmed/34845009
http://dx.doi.org/10.1073/pnas.2026165118