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K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

The mitotic spindle, a self-constructed microtubule-based machine, segregates chromosomes during cell division. In mammalian cells, microtubule bundles called kinetochore fibers (k-fibers) connect chromosomes to the spindle poles. Chromosome segregation thus depends on the mechanical integrity of k-...

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Detalles Bibliográficos
Autores principales: Begley, Marcus A., Solon, April L., Davis, Elizabeth Mae, Sherrill, Michael Grant, Ohi, Ryoma, Elting, Mary Williard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694074/
https://www.ncbi.nlm.nih.gov/pubmed/34668719
http://dx.doi.org/10.1091/mbc.E20-06-0426