Cargando…

K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

The mitotic spindle, a self-constructed microtubule-based machine, segregates chromosomes during cell division. In mammalian cells, microtubule bundles called kinetochore fibers (k-fibers) connect chromosomes to the spindle poles. Chromosome segregation thus depends on the mechanical integrity of k-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Begley, Marcus A., Solon, April L., Davis, Elizabeth Mae, Sherrill, Michael Grant, Ohi, Ryoma, Elting, Mary Williard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694074/ https://www.ncbi.nlm.nih.gov/pubmed/34668719 http://dx.doi.org/10.1091/mbc.E20-06-0426

Ejemplares similares

Synergy between inhibitors of two mitotic spindle assembly motors undermines an adaptive response
por: Solon, April L., et al.
Publicado: (2022)

Mitotic spindle: kinetochore fibers hold on tight to interpolar bundles
por: Tolić, Iva M.
Publicado: (2017)

Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15
por: Malaby, Heidi L.H., et al.
Publicado: (2019)

Force by minus-end motors Dhc1 and Klp2 collapses the S. pombe spindle after laser ablation
por: Zareiesfandabadi, Parsa, et al.
Publicado: (2022)

Force on spindle microtubule minus ends moves chromosomes
por: Elting, Mary Williard, et al.
Publicado: (2014)

The mitotic spindle is chiral due to torques within microtubule bundles
por: Novak, Maja, et al.
Publicado: (2018)

Mitotic spindle scaling during Xenopus development by kif2a and importin α
por: Wilbur, Jeremy D, et al.
Publicado: (2013)

Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment
por: Brouwers, Nathalie, et al.
Publicado: (2017)

Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability
por: Dale, Katie L., et al.
Publicado: (2022)

DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
por: Jang, Chang-Young, et al.
Publicado: (2008)

KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors
por: Terribas, Ernest, et al.
Publicado: (2020)

KIF18A's neck linker permits navigation of microtubule-bound obstacles within the mitotic spindle
por: Malaby, Heidi LH, et al.
Publicado: (2019)

Oblique circle method for measuring the curvature and twist of mitotic spindle microtubule bundles
por: Ivec, Arian, et al.
Publicado: (2021)

Self-organization of kinetochore-fibers in human mitotic spindles
por: Conway, William, et al.
Publicado: (2022)

UV microbeam irradiations of the mitotic spindle. II. Spindle fiber dynamics and force production
Publicado: (1990)

Laser ablation reveals the impact of Cdc15p on the stiffness of the contractile ring
por: Moshtohry, Mohamed, et al.
Publicado: (2022)

Three-dimensional structure of kinetochore-fibers in human mitotic spindles
por: Kiewisz, Robert, et al.
Publicado: (2022)

The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle
por: Welburn, Julie P. I., et al.
Publicado: (2012)

PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
por: Mollinari, Cristiana, et al.
Publicado: (2002)

Concentrating on the mitotic spindle
por: Maddox, Paul S., et al.
Publicado: (2015)

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression
por: O’Regan, Laura, et al.
Publicado: (2015)

Effect of Fiber Bundle Morphology on Fiber Dispersion for Long Fiber-Reinforced Thermoplastics
por: Perez, Hector Sebastian, et al.
Publicado: (2023)

Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Molecule Imaging: Evidence That the Spindle Environment Does Not Stabilize Microtubules
por: Needleman, Daniel J., et al.
Publicado: (2010)

KIF4 helps mitotic chromosomes get in shape
por: Short, Ben
Publicado: (2012)

Pullout Behavior of Bundled Aramid Fiber in Fiber-Reinforced Cementitious Composite
por: Kanakubo, Toshiyuki, et al.
Publicado: (2020)

Force and the spindle: Mechanical cues in mitotic spindle orientation
por: Nestor-Bergmann, Alexander, et al.
Publicado: (2014)

ACTIN AND MYOSIN IN THE MITOTIC SPINDLE
por: Robinson, Richard
Publicado: (2008)

Cell division and the mitotic spindle
por: Inoue, S.
Publicado: (1981)

Microtubule pivoting enables mitotic spindle assembly in S. cerevisiae
por: Fong, Kimberly K., et al.
Publicado: (2021)

Knitting Ripples
por: Daniels, Karen E., et al.
Publicado: (2020)

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle
por: Nixon, Faye M, et al.
Publicado: (2015)

INTERMICROTUBULE BRIDGES IN MITOTIC SPINDLE APPARATUS
por: Hepler, Peter K., et al.
Publicado: (1970)

Mitotic spindle ties the Golgi ribbon
por: Short, Ben
Publicado: (2009)

Systems cell biology of the mitotic spindle
por: Saleem, Ramsey A., et al.
Publicado: (2010)

Adducin-1 moonlights at the mitotic spindle
por: Leslie, Mitch
Publicado: (2014)

How mitotic spindles point to the exit
por: Short, Ben
Publicado: (2018)

Phospho‐regulation of mitotic spindle assembly
por: Ong, Joseph Y., et al.
Publicado: (2020)

Types of potentials in a mitotic spindle
por: Nemchen, Yelena, et al.
Publicado: (2021)

On the assembly of the mitotic spindle, bistability and hysteresis
por: Serpico, Angela Flavia, et al.
Publicado: (2023)

Spindle–F-actin interactions in mitotic spindles in an intact vertebrate epithelium
por: Kita, Angela M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_67427ltug6sepchr8ci7h08hu7