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The two-hit theory hits 50

Few ideas in cancer genetics have been as influential as the “two-hit” theory of tumor suppressors. This idea was introduced in 1971 by Al Knudson in a paper in the Proceedings of the National Academy of Science and forms the basis for our current understanding of the role of mutations in cancer. In...

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Detalles Bibliográficos
Autor principal: Chernoff, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694077/
https://www.ncbi.nlm.nih.gov/pubmed/34735271
http://dx.doi.org/10.1091/mbc.E21-08-0407