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Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants

The electron transport chain (ETC) is a well-studied and highly conserved metabolic pathway that produces ATP through generation of a proton gradient across the inner mitochondrial membrane coupled to oxidative phosphorylation. ETC mutations are associated with a wide array of human disease conditio...

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Detalles Bibliográficos
Autores principales: Lewis, Alisha G., Caldwell, Robert, Rogers, Jason V., Ingaramo, Maria, Wang, Rebecca Y., Soifer, Ilya, Hendrickson, David G., McIsaac, R. Scott, Botstein, David, Gibney, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694083/
https://www.ncbi.nlm.nih.gov/pubmed/34668730
http://dx.doi.org/10.1091/mbc.E21-06-0314